Este artículo es originalmente publicado en:
Ravi B1, Croxford R, Austin PC, Lipscombe L, Bierman AS, Harvey PJ, Hawker GA.
BMJ. 2013 Oct 30;347:f6187. doi: 10.1136/bmj.f6187.
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The relation between total joint arthroplasty and risk for serious cardiovascular events in patients with moderate-severe osteoarthritis: propensity score matched landmark analysis
Relación entre la artroplastia total de la articulación y el riesgo de eventos cardiovasculares graves en pacientes con osteoartritis moderada-grave: puntuación de la propensión igualados al análisis histórico.
To examine whether total joint arthroplasty of the hip and knee reduces the risk for serious cardiovascular events in patients with moderate-severe osteoarthritis.
Propensity score matched landmark analysis.
2200 adults with hip or knee osteoarthritis aged 55 or more at recruitment (1996-98) and followed prospectively until death or 2011.
MAIN OUTCOME MEASURE:
Rates of serious cardiovascular events for those who received a primary total joint arthroplasty compared with those did not within an exposure period of three years after baseline assessment.
The propensity score matched cohort consisted of 153 matched pairs of participants with moderate-severe arthritis. Over a median follow-up period of seven years after the landmark date (start of the study), matched participants who underwent a total joint arthroplasty during the exposure period were significantly less likely than those who did not to experience a cardiovascular event (hazards ratio 0.56, 95% confidence interval 0.43 to 0.74, P<0.001). Within seven years of the exposure period the absolute risk reduction was 12.4% (95% confidence interval 1.7% to 23.1%) and number needed to treat was 8 (95% confidence interval 4 to 57 patients).
Using a propensity matched landmark analysis in a population cohort with advanced hip or knee osteoarthritis, this study found a cardioprotective benefit of primary elective total joint arthroplasty.
Can joint replacement reduce cardiovascular risk? [BMJ. 2013]
The relation between total joint arthroplasty and risk for serious cardiovascular events in patients with moderate-severe osteoarthritis: propensity score matched landmark analysis. [Br J Sports Med. 2014]
PMID: 24174640 [PubMed – indexed for MEDLINE]
Free PMC Article