Abr 27

Efecto de la microfractura en la curación de un desgarre de menisco en un modelo (Capra hircus) Caprino / Effect of Microfracture on Meniscal Tear Healing in a Goat (Capra hircus) Model

Este artículo es originalmente publicado en:




Howarth WR, Brochard K, Campbell SE, Grogan BF.

Orthopedics. 2016 Mar 1;39(2):105-10. doi: 10.3928/01477447-20160119-04. Epub 2016 Jan 25.

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Copyright 2016, SLACK Incorporated.



Meniscal injuries are an extremely common cause of knee pain. Meniscal repairs performed with concomitant anterior cruciate ligament reconstruction appear to heal at a higher rate than meniscal repairs performed in isolation. This may be due in part to the release of marrow elements into the knee and the time of meniscal repair. In cases of isolated meniscal repair, some orthopedic surgeons use microfracture to release marrow elements into the joint as an adjunct to enhance meniscal healing. This study evaluated rates of meniscal tear healing with or without the performance of microfracture in a goat (Capra hircus) model. Forty castrated young adult male goats underwent either a horizontal or a longitudinal 1.0-cm meniscal tear with or without microfracture. All procedures were performed open, in a bloodless field. Meniscal tears were created in the peripheral half of the body of the medial meniscus. The goats were euthanized at 6 months, and meniscal tears were analyzed and classified as complete healing, partial healing, or no healing by direct visualization. A probe was used as an aid to evaluate and classify the meniscal tears. Twenty (87%) of 23 goat meniscal tears showed at least partial healing when performed with concomitant microfracture. Only 5 (29%) of 17 menisci showed any healing in goats that did not receive microfracture. This difference in healing rates was statistically significant (P<.001). Fifteen (65%) meniscal tears accomplished with microfracture were completely healed, whereas only 2 (12%) menisci showed complete healing without microfracture (P<.001). The results of this study suggest that the release of bone marrow elements into the knee by microfracture improves meniscal healing rates. [Orthopedics. 2016; 39(2):105-110.].


Las lesiones de menisco son una causa muy común de dolor en la rodilla. reparaciones de menisco realizados con anterior concomitante reconstrucción del ligamento cruzado parecen curar a una velocidad más alta que las reparaciones de menisco realizados en forma aislada. Esto puede ser debido en parte a la liberación de elementos ósea en la rodilla y el momento de la reparación de menisco. En los casos de reparación meniscal aislado, algunos cirujanos ortopédicos usan microfractura para liberar los elementos de la médula en la articulación como un complemento para mejorar la curación de menisco. Este estudio tasas de curación evaluados desgarro meniscal con o sin el rendimiento de microfractura en un modelo de cabra (Capra hircus). Cuarenta castrados machos adultos jóvenes fueron sometidos ya sea horizontal o longitudinal rotura del menisco de 1,0 cm con o sin microfractura. Todos los procedimientos se realizaron abierta, en un campo sin sangre. las roturas de menisco se crearon en la mitad periférica del cuerpo del menisco medial. Las cabras fueron sacrificados a los 6 meses, y se analizaron y se clasifican como curación completa, cicatrización parcial, o ninguna curación mediante la visualización directa roturas de menisco. Una sonda se utiliza como ayuda para evaluar y clasificar las roturas de menisco. Veinte (87%) de 23 de cabra roturas de menisco mostró la curación al menos parcial, cuando se realiza con microfractura concomitante. Sólo 5 (29%) de 17 meniscos mostró ninguna cicatrización en las cabras que no recibieron microfractura. Esta diferencia en las tasas de curación fue estadísticamente significativa (p <0,001). Quince (65%) las roturas de menisco realizados con microfractura se curaron completamente, mientras que sólo 2 (12%) meniscos mostró curación completa sin microfractura (P <0,001). Los resultados de este estudio sugieren que la liberación de elementos de médula ósea en la rodilla por microfractura mejora las tasas de curación de menisco.

Copyright 2016, SLACK Incorporated.

PMID: 26811956 [PubMed – in process]


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